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RNA methylation plays a significant role as an epigenetic mechanism. N6-methyladenosine (m6A) is the most common and abundant methylation modification in RNA molecules present in eukaryotes. 5-methylcytosine (5-mC) also commonly occurs in various RNA molecules. Recent data strongly suggest that m6A and 5-mC RNA methylation affects the regulation of various biological processes such as RNA stability and mRNA translation, and that abnormal RNA methylation contributes to etiology of human diseases.
A number of kits developed by our partner Epigentek are offered for RNA methylation analysis. For absorbance-based quantitation of N6-methyladenosine in RNA in an ELISA-like format, choose the EpiQuik m6A RNA Methylation Quantification Kit (Colorimetric).

EpiQuik m6A RNA Methylation Quantification Kit (Colorimetric)

  • Colorimetric ELISA-like assay - based on an m6A antibody
  • Fast procedure - completed within 3 hours and 45 minutes
  • High sensitivity - detection limit as low as 10 pg of m6A
  • High specificity - no cross-reactivity to unmethylated adenosine
  • Unique binding solution - m6A quantification from both mRNA and ncRNA

*Expires 28 April 2017

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