Pooled shRNA Libraries
GeneNet Pooled Lentiviral shRNA Libraries are ideal for performing genome-wide screens for genes regulating cellular responses or signaling pathways.
DECIPHER Pooled Lentiviral shRNA Libraries are compatible with the Illumina HT sequencing platform to facilitate positive identification of shRNAs.
HuSH-29 Lentiviral shRNA constructs are sets of 4 unique 29mer shRNA constructs in the lentiviral GFP vector pGFP-C-shLenti. The 29-mer short hairpin design has been demonstrated to be more effective than shorter shRNA versions. Genome-wide coverage for human, mouse and rat.
PLATINUM Select MLP Retroviral microRNA-adapted shRNA constructs are next generation vector-based RNAi triggers generated using the proprietary shERWOOD algorithm developed in Dr. Gregory Hannon’s laboratory at Cold Spring Harbor Laboratory. Use the Transomic Fetch My Gene™ search tool to find shRNA-mir targeting your gene of interest.
Custom shRNA Knockdown Constructs
Our partner Cellecta provides complete services for custom constructs expressing shRNA targeted to any transcript. The constructs are provided in lentiviral vectors.
iLenti Lentiviral siRNA Expression Vectors for the expression of 27-29 bp double-stranded siRNA in vivo are provided as premade or customized constructs for any gene of your choice.
shRNA and siRNA Delivery
Lentiviral Packaging Systems are provided for the generation of pseudoviral particles with high titers for effective gene silencing even in primary and non-dividing cells.siRNA Transfection Reagents especially developed for efficient delivery of siRNA even into hard-to-transfect adherent cells like adipocytes are offered.
Clones from the comprehensive Full-Length cDNA Collections can be used to rescue a loss-of-function phenotype by expressing an orthologous gene from a related species.