Product CartHuman shRNA Libraries (Lentiviral)
GeneNet Lentiviral shRNA Libraries
- Screen genome-wide or focused on gene families for genes regulating cellular responses or signaling pathways
- Identify potential drug targets or diagnostic markers that inhibit, enhance, or activate a selectable phenotype
- Find crucial regulatory genes using routine growth selections or flow sorting
- Cost-effective genome-wide functional analysis at prices affordable to basic researchers
- Focused libraries with lower complexity also available
- Available in FIV- and HIV-based vectors
- Mouse Libraries also available (see link below)
GeneNet siRNA Libraries enable you to perform high-throughput gene knockdown studies on a genome-wide basis or focused on gene families. You can simultaneously identify multiple genes that alter a specific cellular phenotype—in a single experiment.
By merging effector expression libraries with siRNA technology and the efficiency of lentiviral transduction, GeneNet Libraries enable you to conveniently introduce and see the effect of many thousands of siRNA molecules on cell functions at once.
After selecting transduced cells that express a desired phenotype (such as resistance to apoptosis or irradiation, or a growth response to a chemical additive, etc.), you can identify the sets of genes that control the response.
References
Hattori, H. et al. (2007) RNAi screen identifies UBE2D3 as a mediator of all-trans retinoic acid-induced cell growth arrest in human acute promyelocytic NB4 cells. Blood 110: 640-650.
Hwang G.W. et al. (2007) siRNA-mediated inhibition of phosphatidylinositol glycan Class B (PIGB) confers resistance to methylmercury in HEK293 cells. J Toxicol Sci. 32: 581-583.
Related Links
Mouse Lentiviral shRNA Libraries
Lentivirus Purification and Quantitation Kits
Lentiviral siRNA Expression Vectors
Lentiviral Packaging Kit
Lentiviral Transduction Control
User Manual Genome Wide Libraries
User Manual Focused Libraries
List of Target Genes Human 50k siRNA Library
List of Target Genes Human 8.5k siRNA Library
List of Target Genes Human Apoptosis siRNA Library
List of Target Genes Human Kinases siRNA Library
List of Target Genes Human Phosphatases siRNA Library
GeneNet Library Brochure
| Description | Cat# | Size | Price | ||
|---|---|---|---|---|---|
| GeneNet Human 50K siRNA Lentiviral (FIV) Library in pSIF-H1-copGFP (Delivered as plasmid library, 200.000 siRNA targeting 47.400 genes, copGFP selection) | SI205PB-1-SBI | Plasmid Library (200 ug) | please inquire € | DETAILS |
|
| GeneNet Human 50K siRNA Lentiviral (FIV) Library in pSIF-H1-copGFP (Pseudoviral packaged library, 200.000 siRNA targeting 47.400 genes, copGFP selection) | SI205B-1-GVO-SBI | 2 x 10^7 ifu, 2-3 Transductions | 6874 € | DETAILS |
|
| GeneNet Human 50K siRNA Lentiviral (FIV) Library in pSIF-H1-Puro (delivered as plasmid library, 200.000 siRNA targeting 47.400 genes, Puro selection) | SI206PB-1-SBI | Plasmid Library (200 ug) | please inquire € | DETAILS |
|
| GeneNet Human 50K siRNA Lentiviral (FIV) Library in pSIF-H1-Puro (Pseudoviral packaged library, 200.000 siRNA targeting 47.400 genes, Puro selection) | SI206B-1-GVO-SBI | 2 x 10^7 ifu, 2-3 Transductions | 6874 € | DETAILS |
|
| GeneNet Human 50K siRNA Lentiviral (HIV) Library in pSIH-H1-Puro (HIV) (delivered as plasmid library, 200.000 siRNA targeting 47.400 genes, Puro selection) | SI606PB-1-SBI | Plasmid Library (200 ug) | please inquire € | DETAILS |
|
| GeneNet Human 50K siRNA Lentiviral (HIV) Library in pSIH-H1-Puro (Pseudoviral packaged library, 200.000 siRNA targeting 47.400 genes, Puro selection) | SI606B-1-GVO-SBI | 2 x 10^7 ifu, 2-3 Transductions | 6874 € | DETAILS |
|
| GeneNet Human Apoptosis siRNA Lentiviral (HIV) Library in pSIH1-H1-Puro (delivered as plasmid library, 6876 siRNA targeting 579 genes, Puro selection) | SI616PA-1-SBI | Plasmid Library (200 ug) | please inquire € | DETAILS |
|
| GeneNet Human Apoptosis siRNA Lentiviral (HIV) Library in pSIH1-H1-Puro (Pseudoviral packaged library, 6876 siRNA targeting 579 genes, Puro selection) | SI616VA-1-GVO-SBI | 20 x 10^6 ifu (4 x 25 ul) | 3574 € | DETAILS |
|
| GeneNet Human Kinase siRNA Lentiviral (HIV) Library in pSIH1-H1-Puro (delivered as plasmid library, 10453 siRNA targeting 897 genes, Puro selection) | SI626PA-1-SBI | Plasmid Library (200 ug) | please inquire € | DETAILS |
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| GeneNet Human Kinase siRNA Lentiviral (HIV) Library in pSIH1-H1-Puro (Pseudoviral packaged library, 10453 siRNA targeting 897 genes, Puro selection) | SI626VA-1-GVO-SBI | 20 x 10^6 ifu (4 x 25 ul) | 3574 € | DETAILS |
|
| GeneNet Human Phosphatase siRNA Lentiviral (HIV) Library in pSIH1-H1-Puro (delivered as plasmid library, 2719 siRNA targeting 244 genes, Puro selection) | SI636PA-1-SBI | Plasmid Library (200 ug) | please inquire € | DETAILS |
|
| GeneNet Human Phosphatase siRNA Lentiviral (HIV) Library in pSIH1-H1-Puro (Pseudoviral packaged library, 2719 siRNA targeting 244 genes, Puro selection) | SI636A-1-GVO-SBI | 20 x 10^6 ifu (4 x 25 ul) | 3574 € | DETAILS |
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