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Home -> Protein Analysis -> Transcription Factor Activity -> LightSwitch Biomarker and Pathway Sets

LightSwitch Biomarker Promoter Target Sets

Promoter Reporter Construct Pathway Sets selected by motif analysis, and experimentally validated as strongly reacting targets by pathway-specific inductions creating pathway activity profiles. Negative/background controls included in the sets.

Description Cat# Size Price    
LightSwitch GoClone AR (Androgen Receptor) Validated Biomarker Set of Promoter Reporter Constructs (8 top-responding promoters and 2 negative random promoter controls) AR_10-05-SW 10 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone CREB/cAMP Signaling Pathway Validated Biomarker Set of Promoter Reporter Constructs (8 top-responding promoters and 2 negative controls/1 random, 1 housekeeping) CREB10-05-SW 10 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone ER (Estrogen Receptor) Validated Biomarker Set of Promoter Reporter Constructs (8 top-responding promoters and 2 negative random promoter controls) ER_10-05-SW 10 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone GR (Glucocorticoid Receptor) Validated Biomarker Set of Promoter Reporter Constructs (8 top-responding promoters and 2 negative random promoter controls) GR_10-05-SW 10 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone HSF/ Heat Shock Pathway Validated Biomarker Set of Promoter Reporter Constructs (8 top-responding promoters and 2 negative housekeeping gene promoter controls) HS70-05-SW 10 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone Hypoxia (HIF1a) Pathway Validated Biomarker Set of Promoter Reporter Constructs (8 top-responding promoters and 2 negative random promoter controls) HYP10-05-SW 10 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone NF-kB Pathway Validated Biomarker Set of Promoter Reporter Constructs (8 top-responding promoters and 2 negative housekeeping gene promoter controls) NFKB10-05-SW 10 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone p53 Pathway Validated Biomarker Set of Promoter Reporter Constructs (8 top-responding promoters and 2 negative random promoter controls) P53_10-05-SW 10 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone SREBP/Cholesterol Biosynthesis Pathway Validated Biomarker Set of Promoter Reporter Constructs (8 top-responding promoters and 2 negative random promoter controls) SREBP10-05-SW 10 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone SRF (Serum Response Factor) Pathway Validated Biomarker Set of Promoter Reporter Constructs (4 top-responding promoters and 2 negative random promoter controls) SRF10-05-SW 6 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone STAT1/Interferon Response Pathway Validated Biomarker Set of Promoter Reporter Constructs (8 top-responding promoters and 2 negative random promoter controls) STAT10-05-SW 10 x 5ug transfection-ready DNA DETAILS Order


LightSwitch GoClone Promoter Profiling Plates

88 pathway related Promoter Reporter Constructs selected by motif analysis, and experimentally validated by pathway-specific inductions creating complete pathway activity profiles. In order to build a pathway profiling panel, SwitchGear indentified a set of promoters that are often regulated as part of the same signaling pathway yet tend to vary in response to different stimuli. Four negative/background controls and four housekeeping gene promoter controls are also included in the plates.

Description Cat# Size Price    
LightSwitch GoClone AR (Androgen Receptor) Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) AR_96-01-SW 96 x 1ug transfection-ready DNA DETAILS Order
LightSwitch GoClone AR (Androgen Receptor) Large Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) AR_96-05-SW 96 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone CREB/cAMP Signaling Pathway Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) CREB96-01-SW 96 x 1ug transfection-ready DNA DETAILS Order
LightSwitch GoClone CREB/cAMP Signaling Pathway Large Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) CREB96-05-SW 96 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone ER (Estrogen Receptor) Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) ER_96-01-SW 96 x 1ug transfection-ready DNA DETAILS Order
LightSwitch GoClone ER (Estrogen Receptor) Large Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) ER_96-05-SW 96 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone GR (Glucocorticoid Receptor) Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) GR_96-01-SW 96 x 1ug transfection-ready DNA DETAILS Order
LightSwitch GoClone GR (Glucocorticoid Receptor) Large Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) GR_96-05-SW 96 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone Hypoxia (HIF1a) Pathway Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) HYP96-01-SW 96 x 1ug transfection-ready DNA DETAILS Order
LightSwitch GoClone Hypoxia (HIF1a) Pathway Large Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) HYP96-05-SW 96 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone NF-kB Pathway Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) NFKB96-01-SW 96 x 1ug transfection-ready DNA DETAILS Order
LightSwitch GoClone NF-kB Pathway Large Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) NFKB96-05-SW 96 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone p53 Pathway Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) p53_96-01-SW 96 x 1ug transfection-ready DNA DETAILS Order
LightSwitch GoClone p53 Pathway Large Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) p53_96-05-SW 96 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone SREBP/Cholesterol Biosynthesis Pathway Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) SREBP96-01-SW 96 x 1ug transfection-ready DNA DETAILS Order
LightSwitch GoClone SREBP/Cholesterol Biosynthesis Pathway Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) SREBP96-05-SW 96 x 5ug transfection-ready DNA DETAILS Order
LightSwitch GoClone SREBP/Cholesterol Biosynthesis Pathway Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) STAT96-01-SW 96 x 1ug transfection-ready DNA DETAILS Order
LightSwitch GoClone STAT1/Interferon Response Pathway Large Profiling Plate of Promoter Reporter Constructs (88 promoter constructs and 8 controls) STAT96-05-SW 96 x 5ug transfection-ready DNA DETAILS Order

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